Skin Byproducts of Reinhardtius hippoglossoides (Greenland Halibut) as Ecosustainable Source of Marine Collagen

Collagen is a ubiquitous protein present in the extracellular matrix of all major metazoan animals, with approximately 28 different human collagen types described literature, each unique physicochemical properties. Collagens found broad application cosmeceutical, pharmaceutical, and biomedical fields can be isolated from environmentally sustainable sources such as marine byproducts, which are abundant fish processing industry highly appealing low-cost sources. In this study, was skins Greenland halibut (Reinhardtius hippoglossoides), an unexplored byproduct plants, using three extraction methods, due to use distinct salting-out methods solution 2.6 M NaCl + 0.05 Tris-HCl pH = 7.5, (method I); combination 0.7 followed by 2.3 7.5 II); one method only 0.9 III), yielding COLRp_I, COLRp_II, COLRp_III collagens. These extracted type I collagens were produced yield around 2 4% characterized regarding properties, considering possible biotechnological applications. This work evidenced that typical triple helix structure conformation preserved but influenced thermal behavior, intrinsic morphology, moisture capacity collagens, interest for application, incorporation ingredient cosmetic formulation. Furthermore, skin byproducts represents high economic value decreasing cost industrial purposes also source uses.